DB2313 is a potent inhibitor of transcription factor PU.1. DB2313 inhibits PU.1-dependent reporter gene transactivation with an IC50 of 5 µM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis in acute myeloid leukemia (AML) cells and has anticancer effects[1].
Molecular Weight:
708.83
Purity:
99.48
CAS Number:
[2170606-74-1]
Formula:
C42H41FN8O2
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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