ALE-0540, a nonpeptidic small molecule, is a nerve growth factor receptor antagonist. ALE-0540 inhibits the binding of NGF to tyrosine kinase (Trk) A or both p75 and TrkA with IC50 values of 5.88 µM and 3.72 µM, respectively. ALE-0540 can be used to examine mechanisms leading to the development of agents for the study of pain[1].
Molecular Weight:
301.25
Purity:
98.24
CAS Number:
[234779-34-1]
Formula:
C14H11N3O5
Target:
Trk Receptor
Application Notes:
MCE Product type: Reference compound
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