OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC50 of 28 nM[1]. OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM[2].
Molecular Weight:
428.97
Purity:
99.74
CAS Number:
[1338545-07-5]
Formula:
C23H25ClN2O2S
Target:
Apoptosis,CDK,TOPK
Application Notes:
MCE Product type: Reference compound
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