DS86760016 is a potent leucyl-tRNA synthetase (LeuRS) inhibitor with activity against multidrug-resistant (MDR) Gram-negative bacteria, such as Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. DS86760016 inhibits LeuRS enzymes from Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii, with IC50s of 0.38, 0.62, and 0.16 µM, respectively[1][2].
Molecular Weight:
243.45
Purity:
99.25
CAS Number:
[1853176-89-2]
Formula:
C9H11BClNO4
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound
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