TR-100 is a small molecule inhibitor of tumor-associated troponin (Tpm). TR-100 affects the interaction of Tpm3.1 with actin filaments by binding to the C-terminal of Tpm3.1, thereby affecting the stability and function of the actin filaments. This mechanism of action allows TR-100 to specifically affect actin filaments in cancer cells without compromising heart muscle function. TR-100 can be used to study the role of Tpm3.1 in cancer cell proliferation and survival and the effects of Tpm3.1 on insulin-stimulated glucose uptake and insulin secretion[1][2].
Molecular Weight:
422.61
Purity:
99
CAS Number:
[1128165-86-5]
Formula:
C26H38N4O
Target:
Arp2/3 Complex
Application Notes:
MCE Product type: Reference compound
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