MRK-A is a selective, blood-brain-barrier permeable mutant IDH1 inhibitor with an IC50 value of 5 nM. MRK-A inhibits 2-HG production. MRK-A has anti-cancer activity against brain tumors[1].
Molecular Weight:
454.56
CAS Number:
[1934301-68-4]
Formula:
C28H30N4O2
Target:
Isocitrate Dehydrogenase (IDH)
Application Notes:
MCE Product type: Reference compound
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