Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 µM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect[1].
Molecular Weight:
359.81
Purity:
99.27
CAS Number:
[431996-53-1]
Formula:
C18H18ClN3O3
Target:
Fungal
Application Notes:
MCE Product type: Reference compound1
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