ML372 inhibits survival motor neuron (SMN) protein ubiquitination, increases SMN protein stability without affecting mRNA expression. ML372 improves spinal muscular atrophy (SMA) in mice. ML372 is brain penetrant and has a reasonable exposure and half-life in vivo[1].
Molecular Weight:
360.43
Purity:
99.17
CAS Number:
[1331745-61-9]
Formula:
C18H20N2O4S
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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