ENMD-1068 is a selective protease-activated receptor 2 (PAR2) antagonist. ENMD-1068 reduces hepatic stellate cell activation and collagen expression by inhibiting TGF-beta1/Smad signaling. ENMD-1068 also inhibits the proliferation of endometrial cells and induces apoptosis of epithelial cells in the lesion. ENMD-1068 can be used in the study of endometriosis and liver fibrosis[1][2].
Molecular Weight:
283.41
CAS Number:
[789488-77-3]
Formula:
C15H29N3O2
Target:
Apoptosis,Protease Activated Receptor (PAR)
Application Notes:
MCE Product type: Reference compound1
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