hSMG-1 inhibitor 11e is a potent and selective hSMG-1 kinase inhibitor with an IC50 of 900-fold selectivity over mTOR (IC50 of 45 nM), PI3Kalpha/gamma (IC50s of 61 nM and 92 nM) and CDK1/CDK2 (IC50s of 32 µM and 7.1 µM)[1].
Molecular Weight:
517.60
Purity:
99.94
CAS Number:
[1402452-10-1]
Formula:
C26H27N7O3S
Target:
CDK,mTOR,PI3K
Application Notes:
MCE Product type: Reference compound
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