Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen binding site on Hsp47 (IC50=1.8 µM). Col003 discourages the interaction of Hsp47 with collagen and inhibits collagen secretion by destabilizing the collagen triple helix. Col003 can be used for the investigation of fibrosis[1]
Molecular Weight:
257.24
Purity:
99.87
CAS Number:
[328565-16-8]
Formula:
C14H11NO4
Target:
HSP
Application Notes:
Reference compound
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