N.41 is an antiviral agent. N.41 protects APOBEC3G (an antiviral factor) from HIV Vif protein-mediated degradation. N.41 inhibits the Vif-A3G interaction and increases cellular A3G levels and incorporation of A3G into virions, thereby attenuating virus infectivity in a Vif-dependent manner. N.41 inhibits HIV-1 viral replication in PBMCs (IC50: 8.4 µM)[1].
Molecular Weight:
254.28
CAS Number:
[357441-99-7]
Formula:
C15H14N2O2
Target:
HIV
Application Notes:
MCE Product type: Reference compound
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