C1A is a class I/II HDACs and sirtuin inhibitor with an IC50 of 479 nM for HDAC6. C1A induces sustained acetylation of HDAC6 substrates, alpha-tubulin and HSP90. C1A shows srtong anticancer effcts, and induces apoptosis in cancer cells[1].
Molecular Weight:
498.42
CAS Number:
[1021463-02-4]
Formula:
C22H25Cl2N3O4S
Target:
Apoptosis,HDAC,Sirtuin
Application Notes:
MCE Product type: Reference compound
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