NS-1619 is an opener of large conductance Ca2+-activated K+ (BK) channel. NS-1619 is a highly effective relaxant with an EC50 of about 10-30 µM in several smooth muscles of blood vessels and other tissues[1]. NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells[2].
Molecular Weight:
362.23
Purity:
99.32
CAS Number:
[153587-01-0]
Formula:
C15H8F6N2O2
Target:
Apoptosis,Potassium Channel
Application Notes:
MCE Product type: Reference compound1
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