VU6010608 is a blood-brain barrier-crossing mGlu7 negative allosteric modulator (IC50 = 0.76 µM). VU6010608 can block long-term enhancement (LTP) of SC-CA1 synapses in mouse brain slices induced by high-frequency stimulation. VU6010608 can be used for research on neurological diseases[1].
Molecular Weight:
408.33
CAS Number:
[2165325-42-6]
Formula:
C18H15F3N4O4
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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