BMS-986126, CAS [[1610017-20-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-124995
Supplier Catalog Number:
HY-124995
Alternative Catalog Number:
MCE-HY-124995-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
BMS-986126 is a potent, selective, and orally active IRAK4 inhibitor (IC50 = 5.3 nM). BMS-986126 broadly inhibits MyD88-dependent signaling pathways. BMS-986126 demonstrates robust activity in the MRL/lpr and NZB/NZW murine models of lupus, inhibiting multiple pathogenic responses. BMS-986126 can be used for autoimmune diseases research, such as lupus erythematosus (SLE)[1].