JH-IX-179 is an FLT3 inhibitor (IC50 = 4 nM (FLT3-ITD), 10 nM (FLT3-D835Y)). JH-IX-179 inhibits G1 phase arrest and induces apoptosis in FLT3-ITD-expressing cells. JH-IX-179 can be used in acute myeloid leukemia (AML) research[1].
Molecular Weight:
436.51
CAS Number:
[1939104-08-1]
Formula:
C26H24N6O
Target:
Apoptosis,FLT3
Application Notes:
MCE Product type: Reference compound
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