LCH-7749944 (GNF-PF-2356) is a potent PAK4 inhibitor with an IC50 of 14.93 µM. LCH-7749944 effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis[1].
Molecular Weight:
350.41
Purity:
99.68
CAS Number:
[796888-12-5]
Formula:
C20H22N4O2
Target:
Apoptosis,PAK
Application Notes:
MCE Product type: Reference compound
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