KCA-1490 is a dual PDE3/4 inhibitor with IC50 values of 369 nM and 42 nM, respectively. KCA-1490 exhibits potent bronchodilatory and anti-inflammatory activity. KCA-1490 suppresses Histamine (HY-B1204)-induced bronchoconstriction in vivo, which is promising for research of asthma and chronic obstructive pulmonary disease (COPD)[1][2][3].
Molecular Weight:
326.27
CAS Number:
[909719-71-7]
Formula:
C14H13F3N4O2
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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