PHA-680626, CAS [[398493-74-8]] Preis auf Anfrage

Product Overview

• Article Name: PHA-680626, CAS [[398493-74-8]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-125090
• Supplier Catalog Number: HY-125090
• Alternative Catalog Number: MCE-HY-125090-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PHA-680626 is an effective inhibitor of the interaction between Aurora-A and N-Myc. PHA-680626 inhibits kinase activity of AURKA and Bcr-Abl, and induces N-Myc degradation. PHA-680626 decreases phosphorylation of CrkL and histone H3. PHA-680626 shows anti-proliferative and pro-apoptotic activity on Imatinib (HY-15463)-resistant chronic myeloid leukemia cell lines and primary CD34+ cells[1].

Product Properties

• Molecular Weight: 450.56
• CAS Number: [398493-74-8]
• Formula: C23H26N6O2S
• Target: Apoptosis,Aurora Kinase,Bcr-Abl,c-Myc,Histone Methyltransferase

Application Notes

• Application Notes: MCE Product type: Reference compound