SKF-86002 is an orally active p38 MAPK inhibitor, with anti-inflammatory, anti-arthritic and analgesic activities. SKF-86002 inhibits lipopolysaccharide (LPS)-stimulate human monocyte IL-1 and TNF-alpha production (IC50 = 1 µM). SKF-86002 inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid[1][2][3].
Molecular Weight:
297.35
Purity:
99.91
CAS Number:
[72873-74-6]
Formula:
C16H12FN3S
Target:
p38 MAPK
Application Notes:
MCE Product type: Reference compound
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