HOI-07 is a selective Aurora B kinase inhibitor. HOI-07 blocks phosphorylation of histone H3 on Ser10 in lung cancer cells. HOI-07 induces cell-cycle arrest, and apoptosis. HOI-07 has antitumor activity, and suppresses the tumor growth of A549, 143B and KHOS xenografts[1][2].
Molecular Weight:
319.31
CAS Number:
[1451013-67-4]
Formula:
C19H13NO4
Target:
Apoptosis,Aurora Kinase
Application Notes:
MCE Product type: Reference compound
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