IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. IAXO-102 inhibits MAPK and p65 NF-kappaB phosphorylation and expression of TLR4 dependent proinflammatory protein. IAXO-102 also prevents experimental abdominal aortic aneurysm development[1].
Molecular Weight:
585.94
Purity:
98
CAS Number:
[1115270-63-7]
Formula:
C35H71NO5
Target:
Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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