G907 is a selective antagonist of ATP-binding cassette (ABC) transporter MsbA with anti-microbial activity. G907 inhibits E. coli MsbA with an IC50 value of 18 nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket[1][2].
Molecular Weight:
433.93
Purity:
98.06
CAS Number:
[2244035-16-1]
Formula:
C26H24ClNO3
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound
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