PV-1019 (NSC 744039) is a potent, selective Chk2 inhibitor with an IC50 value of 24 nM. PV-1019 inhibits the Topotecan (HY-13768)-induced Chk2 autophosphorylation. PV-1019 inhibits IR-induced apoptosis[1].
Molecular Weight:
379.37
Purity:
99.30
CAS Number:
[1093793-05-5]
Formula:
C18H17N7O3
Target:
Checkpoint Kinase (Chk)
Application Notes:
MCE Product type: Reference compound
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