DJ4 is a ATP-competitive inhibitor of ROCK1/2 (IC50 values:5 and 50 nM) and MRCKalpha/beta (IC50 values:10 and 100 nM). DJ4 blocks stress fiber formation and inhibits migration and invasion of cancer cells. DJ4 can be used for study of lung cancer, breast cancer, and pancreatic (PANC-1) cancer[1].
Molecular Weight:
348.42
Purity:
99.25
CAS Number:
[1681020-24-5]
Formula:
C19H16N4OS
Target:
Cdc42-binding kinase,ROCK
Application Notes:
MCE Product type: Reference compound
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