LEM-14-1189, a LEM-14 (HY-114340) derivative, is a NSDs inhibitor with IC50s of 418 µM (NSD1), 111 µM (NSD2), and 60 µM (NSD3), respectively. The NSDs, histone lysine methyltransferases (HMTases), are oncoproteins, drivers of a number of tumors. LEM-14-1189 can be used for multiple myeloma (MM) research[1].
Molecular Weight:
682.81
Purity:
99.57
CAS Number:
[2987501-17-5]
Formula:
C35H34N6O5S2
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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