(Rac)-Minzasolmin ((Rac)-UCB0599, NPT200-11) is a blood-brain barrier penetrated alpha-synuclein (ASYN) misfolding inhibitor. (Rac)-Minzasolmin acts on the early stage of ASYN aggregation process, by replacing the membrane-bound oligomers ASYN, allowing them to revert to the monomeric form, while preventing pathological aggregation. (Rac)-Minzasolmin effectively improves the ASYN deposition in the retina and the neuro-pathological indicators in two alpha-synuclein transgenic mouse models. (Rac)-Minzasolmin can be used for the studies of Parkinsons disease (PD) and dementia with Lewy bodies (DLB)[1].
Molecular Weight:
425.59
Purity:
99.87
CAS Number:
[1802518-63-3]
Formula:
C23H31N5OS
Target:
alpha-synuclein
Application Notes:
MCE Product type: Reference compound
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