AMG-151 (ARRY-403) is a glucokinase agonist with fasting plasma glucose (FPG) lowering activity. AMG-151 showed a significant linear dose-response trend compared with placebo in a randomized, placebo-controlled Phase IIa study. The use of AMG-151 was associated with a higher incidence of hypoglycemia and hypertriglyceridemia. AMG-151 may serve as a potential compound for the inhibition of type 1 diabetes[1].
Molecular Weight:
454.53
CAS Number:
[1138669-65-4]
Formula:
C20H18N6O3S2
Target:
Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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