Larotaxel (XRP9881) is a taxane analogue with preclinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel[1][2][3].
Molecular Weight:
831.90
Purity:
99.30
CAS Number:
[156294-36-9]
Formula:
C45H53NO14
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound1
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