ToP-DNJ is a selective endoplasmic reticulum alpha-glucosidase II (GluII) inhibitor with an IC50 value of 9.0 µM. ToP-DNJ selectively inhibits the two catalytic reactions of GluII, and exhibits stronger activity in the first step of converting di-glycosylated glycans to mono-glycosylated glycans. ToP-DNJ exhibits anti-DENV activity. ToP-DNJ can be used in studies related to dengue virus infection[1].
Molecular Weight:
661.99
CAS Number:
[1508303-85-2]
Formula:
C40H71NO6
Target:
Dengue Virus,Glycosidase
Application Notes:
MCE Product type: Reference compound
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