DiSBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DiSBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DiSBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.
Molecular Weight:
885.40
CAS Number:
[169211-45-4]
Formula:
C51H88N4O4S2
Target:
Fluorescent Dye
Application Notes:
MCE Product type: Dye Reagents
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