ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 inhibits liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 µM). ICA-105665 can penetrate the blood-brain barrier and has antiseizure effects[1][2][3][4].
Molecular Weight:
355.34
Purity:
99.85
CAS Number:
[2694728-63-5]
Formula:
C19H15F2N3O2
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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