UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor, binds in the MerTK ATP pocket, with an IC50 of 4.4 nM, more selective over Axl, Tyro3 and Flt3. UNC2541 inhibits phosphorylated MerTK (pMerTK, EC50, 510 nM). UNC2541 abolishes the analgesic and anti-inflammatory effects of ozone in vivo and in vitro[1][2][3].
Molecular Weight:
471.57
Purity:
99.71
CAS Number:
[1612782-86-1]
Formula:
C24H34FN7O2
Target:
TAM Receptor
Application Notes:
MCE Product type: Reference compound
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