Phthalazinone pyrazole, CAS [[880487-62-7]]

Product Overview

• Article Name: Phthalazinone pyrazole, CAS [[880487-62-7]]
• Biozol Catalog Number: MCE-HY-12564
• Supplier Catalog Number: HY-12564
• Alternative Catalog Number: MCE-HY-12564-10MG,MCE-HY-12564-25MG,MCE-HY-12564-50MG,MCE-HY-12564-100MG,MCE-HY-12564-5MG,MCE-HY-12564-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Phthalazinone pyrazole is a potent, selective, and orally active inhibitor of Aurora-A kinase with an IC50 of 0.031 µM. Phthalazinone pyrazole can arrests mitosis and subsequently inhibit tumor growth via apoptosis of proliferating cells. Phthalazinone pyrazole suppresses the epithelial-mesenchymal transition (EMT) during the differentiation of hepatocyte-like cells (HLCs) from human embryonic stem cells[1][2].

Product Properties

• Molecular Weight: 317.34
• Purity: 98
• CAS Number: [880487-62-7]
• Formula: C18H15N5O
• Target: Apoptosis,Aurora Kinase,Mitosis

Application Notes

• Application Notes: MCE Product type: Reference compound