BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model. BMX-001 reduces apoptosis in human and murine islets. BMX-001 significantly improves static-glucose stimulated insulin secretion (sGSIS) responses in murine islets. BMX-001 can significantly restore euglycemia in murine islet studies in the presence of the MnSOD. BMX-001 reduces the generation of ROS in a murine islet isolation and culture model[1].
Molecular Weight:
1253.54
CAS Number:
[1379783-91-1]
Formula:
C64H76Cl5MnN8O4
Target:
Apoptosis,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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