PA1 is a photoswitchable epithelial sodium channel (ENaC) blocker. PA1 can switch to cis-PA1 at 400nm and trans-PA1 at 500nm. PA1 inhibits delta/alphaENaC, alphabetagammaENaC, and deltabetagammaENaC, with IC50 values of 4.3nM, 90 nM, and 390 nM, respectively[1].
Molecular Weight:
409.83
CAS Number:
[1620951-72-5]
Formula:
C18H16ClN9O
Target:
Sodium Channel
Application Notes:
MCE Product type: Reference compound
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