SHetA2 is a derivative of heteroarotinoid, that exhibits cytotoxicity in cancer cells with IC50 of 0.37-4.6 µM. SHetA2 regulates cancer cells differentiation, induces apoptosis through the intrinsic mitochondrial pathway, and arrest cell cycle at G2 phase. SHetA2 exhibits good pharmacokinetic characteristics and antitumor efficacy in mice. SHetA2 is orally active[1][2].
Molecular Weight:
401.55
Purity:
99.70
CAS Number:
[361483-66-1]
Formula:
C20H23N3O2S2
Target:
Apoptosis,Caspase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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