BI-3406 (compound I-6) is an orally active, highly potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with an IC50 of 6 nM. BI-3406 potently reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling. BI-3406 has anticancer activity[1][2].
Molecular Weight:
462.46
Purity:
99.95
CAS Number:
[2230836-55-0]
Formula:
C23H25F3N4O3
Target:
p38 MAPK,Ras,SOS1
Application Notes:
MCE Product type: Reference compound1
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