J30-8 is a potent and isoform-selective inhibitor of c-Jun N-terminal kinase 3 (JNK3) with an IC50 of 40 nM, which 2500-fold isoform selectivity against JNK1alpha1 and JNK2alpha2. J30-8 exhibits neuroprotective activity in vitro and potential for the treatment of neurodegenerative diseases[1].
Molecular Weight:
373.79
Purity:
99.51
CAS Number:
[2366255-71-0]
Formula:
C17H9ClFN3O2S
Target:
JNK
Application Notes:
MCE Product type: Reference compound
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