Belzutifan (PT2977) is an orally active and selective HIF-2alpha inhibitor with an IC50 of 9 nM. Belzutifan, as a second-generation HIF-2alpha inhibitor, increases potency and improves pharmacokinetic profile. Belzutifan is a potential treatment for clear cell renal cell carcinoma (ccRCC)[1].
Molecular Weight:
383.34
Purity:
99.85
CAS Number:
[1672668-24-4]
Formula:
C17H12F3NO4S
Target:
HIF/HIF Prolyl-Hydroxylase
Application Notes:
MCE Product type: Reference compound
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