(S,R,S)-AHPC, CAS [[1448297-52-6]]

Product Overview

• Article Name: (S,R,S)-AHPC, CAS [[1448297-52-6]]
• Biozol Catalog Number: MCE-HY-125845
• Supplier Catalog Number: HY-125845
• Alternative Catalog Number: MCE-HY-125845-10MMX1ML,MCE-HY-125845-1G,MCE-HY-125845-5G,MCE-HY-125845-500MG,MCE-HY-125845-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: VH032-NH2, VHL ligand 1

Product Description

(S,R,S)-AHPC (VH032-NH2) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 µM in Ba/F3 cells[1].

Product Properties

• Molecular Weight: 430.56
• Purity: 99.13
• CAS Number: [1448297-52-6]
• Formula: C22H30N4O3S
• Target: Ligands for E3 Ligase

Application Notes

• Application Notes: MCE Product type: Reference compound