TP-008, a chemical probe, is a potent, selective and orally active (Activin-Like Kinase 5) ALK5 inhibitor with pIC50 and pEC50 values of 7.6 and 6.63, respectively. TGFbetaRI-IN-2 can produce observed cardiac toxicity in vivo at high dose[1].
Molecular Weight:
411.82
Purity:
99.42
CAS Number:
[1976038-41-1]
Formula:
C20H15ClFN5O2
Target:
TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound1
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