MI-1061 is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM, Ki=0.16 nM). MI-1061 potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity[1].
Molecular Weight:
582.45
Purity:
99.08
CAS Number:
[1410737-34-6]
Formula:
C30H26Cl2FN3O4
Target:
Apoptosis,E1/E2/E3 Enzyme,MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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