8-Aminoadenosine (8-NH2-Ado), a RNA-directed nucleoside analogue, reduces cellular ATP levels and inhibits mRNA synthesis. 8-Aminoadenosine blocks Akt/mTOR signaling and induces autophagy and apoptosis in a p53-independent manner. 8-Aminoadenosine has antitumor activity[1][2][3].
Molecular Weight:
282.26
Purity:
99.94
CAS Number:
[3868-33-5]
Formula:
C10H14N6O4
Target:
Akt,Apoptosis,Autophagy,DNA/RNA Synthesis,mTOR
Application Notes:
Reference compound
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