Paritaprevir (ABT-450) is a potent, orally active and antiviral non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.31 µM. Paritaprevir is metabolized primarily by cytochrome P450 (CYP) 3A. The plasma concentration and half-life of Paritaprevir can be enhanced by Ritonavir (a CYP450 inhibitor)[1][2][3][4].
Molecular Weight:
765.88
Purity:
99.87
CAS Number:
[1216941-48-8]
Formula:
C40H43N7O7S
Target:
HCV,HCV Protease,SARS-CoV
Application Notes:
MCE Product type: Reference compound1
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