Aurkin A is an allosteric inhibitor for the interaction between Aurora A Kinase (also known also Aurka) and TPX2, through targeting the TPX2 binding sites with Kd of 3.77 µM. Aurkin A can disrupt polyploidy induced by Alisertib (HY-10971) and increase apoptosis of tumor cells. Aurkin A can be used in research on mitosis and cancer[1][2].
Molecular Weight:
346.15
Purity:
98
CAS Number:
[1534060-58-6]
Formula:
C16H9BrFNO2
Target:
Apoptosis,Aurora Kinase
Application Notes:
Reference compound
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