A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (Ki=4.3 µM), casein kinase II (Ki=5.1 µM) and myosin light chain kinase (MLCK) (Ki=7.4 µM). A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectively[1].
Molecular Weight:
321.22
Purity:
99.75
CAS Number:
[78957-85-4]
Formula:
C12H14Cl2N2O2S
Target:
CaMK,Casein Kinase,PKA,PKC
Application Notes:
Reference compound
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