Ucf-101 is a selective and competitive inhibitor of pro-apoptotic protease Omi/HtrA2, with an IC50 of 9.5 µM for His-Omi. Ucf-101 exhibits very little activity against various other serine proteases (IC50>200 µM). Ucf-101 has a natural red fluorescence at 543 nm that is used to monitor its ability to enter mammalian cells. Ucf-101 has a significant cardioprotective effect against MI/R injury and also has certain neuroprotective effect[1][2][3].
Molecular Weight:
495.51
Purity:
99.65
CAS Number:
[313649-08-0]
Formula:
C27H17N3O5S
Target:
Apoptosis
Application Notes:
Reference compound
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