T3Inh-1 is a potent and selective inhibitor of ppGalNAc-T3 (IC50=7 µM). T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic side effects. T3Inh-1 also prevents breast cancer cells. The enzyme ppGalNAc-T3 is implicated in at least two medically important pathways: cancer metastasis and stabilization of FGF23 (regulates phosphate levels in the bloodstream)[1].
Molecular Weight:
476.49
Purity:
99.93
CAS Number:
[50440-30-7]
Formula:
C27H20N6O3
Target:
Others
Application Notes:
MCE Product type: Reference compound1
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